Oct. 3, 2025
Why Fibromyalgia Isn’t in Your Head: The Science That Changes Everything with Dr. Bruce Gillis
Send us a text For decades, fibromyalgia patients were told their pain was “all in their head.” Dr. Bruce Gillis, Harvard-trained physician and researcher, has changed that narrative with the first blood test to prove fibromyalgia is real. What if the condition you’ve struggled with for years - pain, fatigue, brain fog - wasn’t imaginary, but instead rooted in your immune system? That’s the groundbreaking discovery Dr. Bruce Gillis brings to light in this episode of Raise the Script with Nutr...
For decades, fibromyalgia patients were told their pain was “all in their head.” Dr. Bruce Gillis, Harvard-trained physician and researcher, has changed that narrative with the first blood test to prove fibromyalgia is real.
What if the condition you’ve struggled with for years - pain, fatigue, brain fog - wasn’t imaginary, but instead rooted in your immune system? That’s the groundbreaking discovery Dr. Bruce Gillis brings to light in this episode of Raise the Script with Nutrigenomics.
Dr. Gillis developed the FM/a® Test, the first diagnostic blood test for fibromyalgia, providing biological validation for millions of patients who had been dismissed or misdiagnosed. He reveals how fibromyalgia is not a syndrome, but an immune deficiency disease with measurable DNA and immune system abnormalities.
Together, we explore why fibromyalgia has been stigmatized for decades, how pharmaceutical and economic interests have slowed recognition, and what this breakthrough means for other conditions like long COVID and interstitial cystitis. If you’ve ever felt unheard by the medical system, this conversation offers hope, science, and a new path forward.
What You’ll Learn in This Episode:
- Why fibromyalgia is a legitimate biological disease, not “all in your head”
- How the FM/a® Test detects fibromyalgia through immune system markers
- The connection between fibromyalgia, long COVID, and interstitial cystitis
- How gender bias and stigma have shaped the experience of invisible illness
- The future of diagnostics and targeted immune-based therapies for chronic pain
Resources & Links Mentioned:
- Learn more about the FM/a® Test: FM1Test.com
- Explore the immune-supporting compound IMBXX:
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00:00 - Rethinking Pills And Personalization
01:15 - Show Welcome And Mission
02:45 - Introducing Dr. Bruce Gillis
03:36 - The Stigma And History Of Fibromyalgia
07:40 - Immune Abnormalities And The FM Test
11:04 - Big Pharma Pushback And Validation
14:08 - Ordering FM1Test And Access
15:24 - From Diagnosis To Targeted Immune Support
18:00 - Long COVID Overlap And Viral Triggers
20:37 - Access, Research Invitations, And Cost
22:03 - Economics Of Rule-Out vs Rule-In Testing
23:24 - Microbiome, Gut–Brain Axis, And Med Confounders
25:28 - Practical Next Steps For Patients
27:52 - Future Breakthroughs And Related Conditions
30:18 - Physician Resistance And Patient Advocacy
33:12 - Safety Data And Compound Background
35:01 - Closing Reflections And Calls To Action
36:52 - Final Summary And Resources
WEBVTT
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Medications certainly have their place, but what if there was a way to support your body naturally by working with your genetics?
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We are a pill for an ill society.
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We take 18 pills per person per American per day.
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It was so hard to find somebody who took my insurance.
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And for me to get well, it took thousands of dollars.
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And I thought, though, what do regular people do?
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This is not right.
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Despite my best efforts, I wasn't actually reversing disease and helping people to heal in the way that I thought I would.
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We want to empower yourselves to take care of this root cause.
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We don't just want to cover it up.
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If you're ready to break free from outdated, one-size-fits-all health care, you're in the right place.
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Welcome to Raise the Script with Nutrigenomics, brought to you by InHer Glow® by LYFE Balance.
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Here's a literature from we're all unique, right down to our DNA.
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So it's no wonder we respond differently to the same medications, foods, and environments.
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How do you discover what your body needs?
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Which medications, foods, supplements, or exercises are right for you?
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How can you manage chronic conditions without piling on more prescriptions?
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That's what we're here to explore.
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I'm your host, Dr.
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Tamar Lawful, Doctor of Pharmacy, Nutrigenomics Specialist, and your partner in reimagining how we personalize care for better outcomes.
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Whether you're a patient or a practitioner, let's raise the script and bring health care to higher levels together.
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Because the future of health is personal.
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Hey there, friends.
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Welcome back to Pivoting Pharmacy with Nutrigenomics, where we explore the science, the stories, and the strategies that are reshaping health from the inside out.
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I'm your host, Dr.
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Tamar Lawful, Doctor of Pharmacy.
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Now, let me take you back a few decades.
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Imagine walking into a doctor's office with relentless pain, crushing fatigue, and brain fog so heavy you can barely think.
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Instead of health, you're told it's all in your head.
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That was the reality for millions of people, mostly women, who lived with what came to be called fibromyalgia.
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A name without a test, without answers, and loaded with stigma.
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But here's the truth: it was never all in their heads.
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Their bodies were sounding an alarm, medicine wasn't ready to hear.
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Fast forward to today.
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My guest, Dr.
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Bruce Gillis, is the Harvard-trained physician and researcher who proved it.
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He developed the world's first blood test for fibromyalgia, uncovering immune system abnormalities that explain the very real suffering behind this invisible illness.
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His work is rewriting the story, not just for fibromyalgia, but for chronic pain, long COVID, and other conditions medicine has struggled to understand.
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In our conversation today, you'll hear how he challenged the medical establishment, what the science actually shows, and why hope is finally on the horizon for patients who've been dismissed for far too long.
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This is an episode you don't want to miss, friend.
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So listen in.
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Dr.
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Gillis, thank you for joining me on Raise The Script with Nutrigenomics today.
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It's a pleasure to have you, and I'm looking forward to our conversation.
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I want to thank you very much for having the opportunity to speak to you and your listeners about very important subjects.
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Indeed.
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Now, Dr.
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Gillis, I'm curious to know what first drew you to the world of invisible illnesses like fibromyalgia, conditions that medicine historically overlooked, I could say.
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Number one, uh they purposely overlooked it.
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But number two, I was approached more than 15 years ago by an insurance company who was concerned that they had sold long-term disability policies to people for a healthcare basis.
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And suddenly they were getting claims in from 20-year-olds and 30-year-olds saying they were permanently and totally disabled because of having fibromyalgia.
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And based upon that, I took on the challenge and with colleagues at the University of Illinois College of Medicine, we were able to identify that fibromyalgia is very much a real disease.
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It's not a syndrome, and it's the product of immune system abnormalities.
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You can identify those abnormalities through a simple blood test.
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And over time we have also learned that 100% of people who have a positive fibromyalgia blood test result have unique DNA genomic signatures.
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And therefore, if someone says fibromyalgia isn't real, it is tantamount to saying that DNA isn't real.
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And if that's so, we better let out all those murderers and other uh criminals in prison who were convicted based upon DNA evidence.
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Well, that's interesting.
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And I'm looking forward to diving into that genetic aspect of fibromyalgia.
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Now, you mentioned that maybe intentionally, it's it's been overlooked intentionally.
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And I I want to go into that because fibromyalgia has carried so much stigma.
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Patients are told a stress, or worse, imagined, as you mentioned.
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Now, can we break down that history?
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Why has mainstream medicine been so resistant to recognizing fibromyalgia as a legitimate biological condition?
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I think the first issue is sexism.
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They thought that fibromyalgia was only a disease that was experienced by women.
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And as we know, female gender-related diseases get short shrift in the not just in the United States, but in the world, right?
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Right.
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So that was number one.
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When I entered the field, I was told by many people, particularly physicians, that fibromyalgia was a bogus affliction of neurotic, hypochondriacal, hysterical women.
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When I met with fibromyalgia support groups, I was stunned.
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It was 99.9% women, and they would tell me stories that were beyond belief.
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They would go to the doctor, and the doctor would say, honey, that's the that was a common phrase, honey, it's all in your head.
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Your husband doesn't love you enough, maybe you don't have a good enough sex life, all sorts of terrible, biased comments.
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And I found that extraordinary and terribly insulting.
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As it turns out, we identified the fact through years of research that fibromyalgia is not gender-specific.
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It happens in men as often as in women, and it is not age-specific.
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I have seen people with fibromyalgia as young as age three and certainly into their 80s or 90s.
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So fibromyalgia does exist, and unfortunately, fibromyalgia is a totally made-up name.
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There is nothing wrong with the fibrous or connective tissue.
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There is nothing wrong with the myalgic or muscle tissue.
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The disease has nothing to do with that.
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But what happened is the stigma is actually worse than you can imagine.
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As it turns out, the level of suicide and suicidal ideation in fibromyalgia patients exceeds other illnesses, including mental depression.
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And the reason is, as you already pointed out accurately, doctors don't believe there's anything wrong with these people.
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Terrible.
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So you go to the doctor, they say, Well, we can't find anything wrong with you.
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It's a condition of exclusion.
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We test you for all sorts of other diseases, all those test results are negative, you must have fibromyalgia, and we have no way to quantify it or objectify it.
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Number two, you look perfectly normal.
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So your spouse, your friends and family say, there's something wrong with her in the head, right?
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It's all got to be, you know, an emotional issue.
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And number three, when you get the diagnosis until recently, there was no way to overcome the manifestations of the disease, the brain fog, the discomfort, the poor sleep, the negative emotional thoughts, the chronic fatigue.
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And unfortunately, despite all of the major discoveries and breakthroughs we have made, I'm still fighting an uphill battle.
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Part of that is because the FDA decided to approve an anti-seizure medicine and two antidepressant medications and said they were specified for fibromyalgia.
00:09:06.639 --> 00:09:09.440
But fibromyalgia doesn't cause seizures.
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Seizure disorders have nothing to do with fibromyalgia.
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And if you get fibromyalgia, you become depressed.
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But depression doesn't give you fibromyalgia.
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So those kinds of compounds mask the manifestations of the condition, but don't do anything with the actual pathology of the disease.
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And it is a disease.
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It is not a syndrome.
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A syndrome is defined as a collection of symptoms.
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A disease has objective manifestations.
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And our research has unequivocally proven those manifestations.
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And to this date, there has not been one physician, one scientist, one laboratory who has ever found a fault in the diagnostic test or in the pathways we have identified.
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But yet the criticism remains, and the fibroskepticism remains, and to me is astonishing.
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It is.
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What we found is that people with fibromyalgia have a form of a defective white blood cell.
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You may know when you went to elementary school, you learned about red blood cells and white blood cells.
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And white blood cells circulate to protect you against infections and injuries and inflammation.
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We identified that a specific type of white blood cell called the peripheral blood mononuclear cell has a number of roles in your health.
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One of those roles is to produce important proteins.
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And patients with fibromyalgia have defective peripheral blood mononuclear cells, and as a result, they cannot produce normal quantities of four proteins.
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These proteins are called MIP1 alpha, MIP1 beta, IL6, and IL8.
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We originally did the research at the Department of Pathology at the University of Illinois, and we published the results.
00:11:47.519 --> 00:12:10.639
And at that time there was criticism primarily by physicians who were paid hundreds of thousands of dollars by a very large drug company because our science proved that this drug company's product could do nothing to your immune system, could not impact or benefit your immune system.
00:12:10.639 --> 00:12:15.519
But they were selling their product at billions of dollars per year.
00:12:15.519 --> 00:12:21.360
And as you can understand, I don't have billions of dollars available to compete.
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In fact, one of the doctors who made a criticism on the internet, I contacted and I asked that person directly on what basis do you find a problem with the test?
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And he said to me, I haven't read your research, and I'm not exaggerating.
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That's the level of how big pharma can affect healthcare delivery in this country.
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That's number one.
00:12:48.799 --> 00:12:53.759
The criticism, though, that came up was well, you only did it in one laboratory.
00:12:53.759 --> 00:12:55.919
How do we know your test is accurate?
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It should be reproduced in a second laboratory.
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The University of Illinois College of Medicine and the Department of Pathology is highly ranked and has an important and valuable reputation.
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But despite the unfair criticism, we redid the test through at that time one of the world's foremost rheumatologists, a professor at UCLA, using his patients, using a different laboratory, and guess what?
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We reproduced the results spot on.
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So there is no basis to say that the test isn't accurate.
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And as I already mentioned, to date, the test has now been available for 12 years.
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No physician, no laboratory, no scientist has ever been able to say, oh, the test is inaccurate.
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It's never happened.
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It's never happened.
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And since then, we have done further important research and we proved that 100% of people who have a positive fibromyalgia blood test score have unique DNA genomic signatures, DNA patterns that don't exist in any other disease or in healthy people.
00:14:08.559 --> 00:14:12.000
And if you don't want to believe in my test, fine.
00:14:12.000 --> 00:14:15.279
But that's a tantamount to saying I don't want to believe in DNA.
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That's essentially what we're saying.
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So that's important.
00:14:18.720 --> 00:14:25.759
And as far as the test goes, for the vast majority of people, it costs them nothing because it's covered by health insurance.
00:14:25.759 --> 00:14:32.159
Medicare pays for it, TriCare pays for it, Blue Cross Blue Shield pays for it, private insurance companies pay for it.
00:14:32.159 --> 00:14:38.480
Certainly, if the test wasn't accurate and diagnostic, they wouldn't pay paying for it.
00:14:38.480 --> 00:14:41.679
So for most people, they pay nothing to get the test.
00:14:42.639 --> 00:14:43.600
That's a great point.
00:14:43.600 --> 00:14:48.399
And it's been an uphill battle, but definitely one that's worth it.
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How can practitioners get a hold of the test?
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Is it easy to order?
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How does that work?
00:14:54.720 --> 00:14:56.159
It's very easy to order.
00:14:56.159 --> 00:14:59.759
There's a new test, it's called FM1Test.
00:14:59.759 --> 00:15:03.919
You just go to FM1Test.com, you fill out the form.
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There is a form for your doctor to sign and return.
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We will then send a uh a referral so you can go to any Quest Lab clinic to have your blood drawn.
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We will get the blood back in uh 24 hours or less.
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You'll have your results several days later.
00:15:24.720 --> 00:15:46.480
And if your test is positive, at zero cost, you can volunteer for a 30-day supply of a compound that we developed that causes those defective white blood cells to increase their production of those proteins and therefore reduce and in many cases eliminate your symptoms.
00:15:46.480 --> 00:16:00.080
No money out of pocket, usually for the test, no money to try something that is 100% natural, 100% non-toxic, that can potentially change your life.
00:16:00.080 --> 00:16:03.600
The compound is called Imbix, IMBXX.
00:16:03.600 --> 00:16:12.960
There's a website called Imbix.com, and I recommend people read and watch the videos and the comments by people who have taken it.
00:16:12.960 --> 00:16:14.399
It's astonishing.
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People who have been afflicted for not years but decades saying that their condition has changed, that they don't have the symptoms they previously had.
00:16:24.960 --> 00:16:25.840
Well, that's amazing.
00:16:25.840 --> 00:16:26.799
That's amazing, Dr.
00:16:26.799 --> 00:16:27.519
Gillis.
00:16:27.519 --> 00:16:35.759
Now, along the lines of those treatments, since we're on that topic, I know your team's exploring therapies that based on immune system deficiencies.
00:16:35.759 --> 00:16:41.440
So are you moving towards not just diagnosis but actual targeted treatment for these deficiencies?
00:16:42.320 --> 00:16:53.039
So interestingly, uh uh I came across some research from the 1990s and early 2000s.
00:16:53.039 --> 00:17:00.960
There was a desire to get terminal cancer patients to respond better to anti-cancer drugs.
00:17:00.960 --> 00:17:14.880
And research was done by a variety of teams in Europe, and they came across the fact that there was a family of non-pathologic bacteria that seemed to help promote the immune system.
00:17:14.880 --> 00:17:22.400
Based upon that, I went ahead and tested seven of those bacterial families.
00:17:22.400 --> 00:17:42.079
We published our results, and by the way, everything I've done has been peer-reviewed and published, published in phenomenal journals often, such as Nature, which is, I think, the there's 30,000 medical journals, and I think this is number five, so you can understand the impact of the research we've achieved.
00:17:42.079 --> 00:18:24.160
And what we have been able to prove is that not only do we know the pathways regarding the immune system, in a study, a very small study we did on long COVID patients, we found that nearly nine out of ten people who develop long COVID also develop the same immune deficiencies that exist in fibromyalgia, which means that potentially a virus triggers all of this, that the process of developing those DNA genomic signatures could be triggered by a virus.
00:18:24.160 --> 00:18:27.759
And that's why it's not an age-specific disease.
00:18:27.759 --> 00:18:34.960
And the virus is in a family that are called coronaviruses, which are the leading cause of why you get a common cold.
00:18:34.960 --> 00:18:37.519
So it's easy to have this happen.
00:18:37.839 --> 00:18:46.559
Wow, and thanks for bringing that point out because I was one of the questions I wanted to touch on with you was the long COVID connection, which you've brought out perfectly.
00:18:46.559 --> 00:18:56.640
Now, do you think that long COVID could be the condition that finally forces mainstream medicine to take fibromyalgia seriously?
00:18:57.200 --> 00:19:09.200
Boy, I would hope that it is, but I also have to tell you that the federal government spent $1.5 billion looking for a test to diagnose long COVID.
00:19:09.200 --> 00:19:21.599
And I went to two of the centers that were using some of those dollars, one of which said to me, you know, long COVID patients seem to be the same as fibromyalgia patients.
00:19:21.599 --> 00:19:23.279
They have the same symptoms.
00:19:23.279 --> 00:19:28.079
And I said to them, I said, I'll tell you what, give me a hundred of your patients.
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You pick them, let me test them, and we'll do it for free.
00:19:31.440 --> 00:19:44.480
And they turned me down because I think they were afraid that I would come up with a diagnostic test that they didn't come up with, and it would somehow impact their reputation.
00:19:44.480 --> 00:20:17.039
So we did a small study, again through the University of Illinois College of Medicine, and it's an early study, and it's only early because I don't have enough patients that I want to test, but I invite anybody who is suspected to have long COVID to arrange for the blood test, and we have a sister compound for them to try, again at zero cost, to see if it can in any way change the symptoms that they are experiencing.
00:20:17.039 --> 00:20:20.000
I mean, so I'm doing this essentially for a patient.
00:20:20.000 --> 00:20:23.519
If you're afflicted, it's little to nothing out of pocket.
00:20:23.519 --> 00:20:25.359
What have you got to lose, right?
00:20:25.359 --> 00:20:41.440
And there are about 30 million people with long COVID, and I'm not sure where you're located, but I'm in California, and we're starting to see COVID infections at epidemic proportions, possibly because our government is trying to limit people from getting the COVID vaccine.
00:20:41.759 --> 00:20:52.240
I'm in California as well, and I have come across some coworkers that have long COVID, and yeah, it's definitely something that needs to be addressed.
00:20:52.240 --> 00:21:01.599
So if someone's listening today and they are someone that feels that they may be able to be in your research, how would they get in touch with you?
00:21:01.920 --> 00:21:05.359
All they need to do is they can email me.
00:21:05.359 --> 00:21:10.240
It's BSgm D at CIMSX.com.
00:21:10.240 --> 00:21:17.200
I'll repeat that.com.
00:21:17.200 --> 00:21:21.440
And they can register for the blood test.
00:21:21.440 --> 00:21:25.759
If they have insurance, we'll get verification for their insurance.
00:21:25.759 --> 00:21:28.640
We can arrange for them to have the blood test drawn.
00:21:28.640 --> 00:21:39.440
If the test is positive, if they want to volunteer for a 30-day supply of the compound to see if it impacts their symptoms, that's totally at no cost.
00:21:39.759 --> 00:21:41.279
Okay, thank you for sharing that.
00:21:41.279 --> 00:21:53.920
Now, you've definitely been pushing the boundaries in medicine, and you've also collaborated with some of the biggest names in medicine, Stanford, Mayo Clinic, John Hopkins, and with big breakthroughs, often come big debates.
00:21:53.920 --> 00:21:58.799
What's been the most surprising or controversial finding your research hasn't covered?
00:21:59.200 --> 00:22:11.759
It's uncovered the fact that there are economic forces who don't want to apply the science that we have been able to prove that we've had peer-reviewed and published.
00:22:11.759 --> 00:22:30.799
If you go to a physician and you are suspected to have fibromyalgia, nine times out of ten, the physician is going to put you through what are called rule-out tests, tests that they often can do in their office, and there's an economic benefit to do it in their office.
00:22:30.799 --> 00:22:37.200
And they will say, well, let's test you for rheumatoid arthritis or lupus or other strange diseases.
00:22:37.200 --> 00:22:42.240
In contrast, the FM1 test is a rule-in test.
00:22:42.240 --> 00:22:44.960
It says either you have it or you don't have it.
00:22:44.960 --> 00:22:48.799
It is an accurate way to determine the diagnosis.
00:22:48.799 --> 00:22:55.200
But your doctor can't make any money ordering the tests because it has to be done in a separate laboratory.
00:22:55.200 --> 00:23:08.319
Insurance companies don't allow for the laboratory to reimburse your doctor to draw the blood, so we've now arranged to work with the Quest Clinic system, and their draw stations are all over the United States.
00:23:08.319 --> 00:23:17.039
In fact, Quests will often, if you're far away from them, will send out someone to where you work or where you live to have your blood drawn at no cost.
00:23:17.039 --> 00:23:17.599
Okay?
00:23:18.000 --> 00:23:18.400
That's good.
00:23:18.400 --> 00:23:19.359
So it's convenient.
00:23:19.359 --> 00:23:20.240
No more guessing.
00:23:20.240 --> 00:23:21.519
There's no need to guess anymore.
00:23:21.599 --> 00:23:22.240
We'll come to this.
00:23:22.240 --> 00:23:23.440
That's exactly it.
00:23:23.440 --> 00:23:31.119
And you'll have a piece of paper, a lab report that is a way to substantiate your diagnosis.
00:23:31.119 --> 00:23:44.000
And while there may still be skepticism after you have that piece of paper, you will know in your mind and in your heart, you have an objective evidence and proof for why you have been sick.
00:23:44.000 --> 00:23:49.200
And you also have a pathway now to address the symptoms.
00:23:49.200 --> 00:23:51.279
There is no way to change your DNA.
00:23:51.279 --> 00:23:52.319
You understand.
00:23:52.319 --> 00:23:56.480
We're not promoting or claiming that we have any kind of drug.
00:23:56.480 --> 00:24:00.400
We're not claiming that we're changing your DNA.
00:24:00.400 --> 00:24:06.799
All we're saying is we're working through something that I'm sure you're very familiar with, the microbiome.
00:24:06.799 --> 00:24:14.400
The compound boosts the health of your microbiome and acts on what is called the gut brain axis.
00:24:14.400 --> 00:24:18.960
And through these pathways, oftentimes people get better.
00:24:18.960 --> 00:24:46.880
The only people who don't seem to get better are people who continue to take medicines that can damage your microbiome or mask how your brain reacts, people who, for example, are on narcotics or opiates or antidepressants, et cetera, that can block your brain's ability to respond to the microbiome-induced and improved level of immune system health.
00:24:47.279 --> 00:24:55.039
And that's interesting because most of those patients who have probably been diagnosed with fibromyalgia are already on those medications.
00:24:55.440 --> 00:24:56.960
Yes, and they're no better, right?
00:24:56.960 --> 00:24:58.000
They're not getting any better.
00:24:58.000 --> 00:24:58.960
They're not getting better.
00:24:58.960 --> 00:24:59.920
They're not getting better.
00:24:59.920 --> 00:25:03.839
And I'm saying there's a way to feel better, okay?
00:25:03.839 --> 00:25:10.720
To subjectively feel better because we're boosting the health of your immune system.
00:25:11.200 --> 00:25:12.400
Yeah, amazing.
00:25:12.400 --> 00:25:13.680
This is a great breakthrough.
00:25:13.680 --> 00:25:25.359
I'm glad that we're discussing this and getting it out there, getting this message out there that this test exists for them to have a definitive answer as to what's going on, and then also a solution at hand.
00:25:25.359 --> 00:25:28.240
Now I want to bring this down to the listener.
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